Loperamide (also sold under the brand name Imodium®) is a prescription and over-the-counter (OTC) medicine approved by the U.S. Food and Drug Administration  to relieve the symptoms of diarrhea.

Loperamide is safe at approved doses: a maximum of 8 mg per day for OTC use or as instructed by your healthcare provider.

Taking more than the approved dose can result in serious heart problems and death.

If you or someone you know is taking more than the recommended dose of loperamide and experiences any of the following symptoms, discontinue loperamide use immediately and call emergency services.

  • Fainting

  • Unresponsiveness

  • Irregular heartbeat or chest pain

If you believe that you or someone you know may have a substance use disorder, talk to a healthcare provider and find additional resources at You can also call Substance Abuse and Mental Health Services Administration ’s National Helpline at 1-800-662-4357 for free, confidential treatment referral information.


To learn more about loperamide, visit



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